Vaccine immunology

Clinical and Vaccine Immunology

Limit the abstract to 250 words or fewer and concisely summarize the basic content of the paper without presenting extensive experimental details. Avoid abbreviations and references, and do not include diagrams. When it is essential to include a reference, use the same format as shown for the References section but omit the article title. Conclude the abstract with a summary statement. Because ...

Vaccine Immunology — Types of Vaccines

Reverse vaccinology 2.0: Human immunology instructs vaccine antigen design

Traditionally, vaccines have been developed by cultivating infectious agents and isolating the inactivated whole pathogen or some of its purified components. 20 years ago, reverse vaccinology enabled vaccine discovery and design based on information deriving from the sequence of microbial genomes rather than via the growth of pathogens. Today, the high throughput discovery of protective human a...

Animal Health-Johne’s Disease (JDIP): Basic Biology/Immunology/Vaccine Development

J. Anim. Sci. Vol. 88, E-Suppl. 2/J. Dairy Sci. Vol. 93, E-Suppl. 1/Poult. Sci. Vol. 89, E-Suppl. 1 55 A novel approach to evaluate the cost-benefit of use of Johne’s disease vaccine while considering effects on the bovine tuberculosis eradication program. F. J. Zagmutt*1, L. A. Espejo2, H Groenendaal1, J. R. Lima2, E. Patton3, I. A. Gardner4, and S. Wells2, 1Vose Consulting, Boulder, CO, 2Coll...

South Indian leprosy vaccine trial: important lessons for mycobacterial immunology.

Between January 1991 and July 1 993, 1 7 1 ,400 individuals living in Chingleput District, South India, were recruited into a major leprosy vaccine trial organized by the Indian Council for Medical Research. The participants were randomized to receive a placebo, a plain BCG vaccine, a combination of BCG plus killed leprosy bacilli, or else a killed environmental mycobacterial vaccine : either '...